Product Data Sheet

Casein kinase 1δ-IN-28

Catalog No. A36947

main product photo
Casein kinase 1δ-IN-28 is a selective inhibitor of Casein Kinase 1 (CK1) with an IC50 of 0.0146 μM. This compound demonstrates significant potential for modulating CK1-mediated pathways, making it a valuable tool for studies in cell signaling and cancer research. Additionally, Casein kinase 1δ-IN-28 shows a metabolite rate of 52% in human liver microsomes, indicating its metabolic stability for in vitro applications.
Chemical Information
Catalog NumA36947
M. Wt402.47
FormulaC23H23FN6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1095750-94-9
Synonyms
SMILESFC1=CC=C(C2=C(C3=CC=NC=C3)N4N=C(N5CCNC(C)(C5)C)C=CC4=N2)C=C1
Biological Activity
DescriptionCasein kinase 1δ-IN-28 is a selective inhibitor of Casein Kinase 1 (CK1) with an IC50 of 0.0146 μM. This compound demonstrates significant potential for modulating CK1-mediated pathways, making it a valuable tool for studies in cell signaling and cancer research. Additionally, Casein kinase 1δ-IN-28 shows a metabolite rate of 52% in human liver microsomes, indicating its metabolic stability for in vitro applications.
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