Product Data Sheet
β-Catenin modulator-7
Catalog No. A37126
β-Catenin modulator-7 is a targeted modulator of β-catenin, primarily influencing its expression in the cytoplasm and nucleus of HCT-116 cells. This compound effectively inhibits GSK 3β phosphorylation, promoting nitric oxide release and thereby reducing cancer cell proliferation with an IC50 of 0.6-0.9 μM. β-Catenin modulator-7 is positioned for research applications in studying colon cancer and its associated signaling pathways.
Chemical Information
| Catalog Num | A37126 |
|---|---|
| M. Wt | 583.03 |
| Formula | C26H35ClN4O9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2892294-93-6 |
| Synonyms | |
| SMILES | [O-]/[N+](N(CC)CC)=N\OCOC(CCCCOC1=C(OC)C=C(/C=C/C(N(CCC=C2Cl)C2=O)=O)C=C1OC)=O |
Biological Activity
| Description | β-Catenin modulator-7 is a targeted modulator of β-catenin, primarily influencing its expression in the cytoplasm and nucleus of HCT-116 cells. This compound effectively inhibits GSK 3β phosphorylation, promoting nitric oxide release and thereby reducing cancer cell proliferation with an IC50 of 0.6-0.9 μM. β-Catenin modulator-7 is positioned for research applications in studying colon cancer and its associated signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
