Product Data Sheet

9,10-EpOME

Catalog No. A37212

main product photo
9,10-EpOME (9,10-Epoxyoctadecenoic acid) is a cytochrome P450-derived metabolite of linoleic acid. It is known to induce oxidative stress by activating the NF-κB and AP-1 transcription factors and facilitates the chemotaxis of human neutrophils. Additionally, 9,10-EpOME has been shown to induce mechanical and thermal pain in wild-type mice via the PKA pathway. This compound is useful for investigating mechanisms of inflammation and pain in research settings.
Chemical Information
Catalog NumA37212
M. Wt296.44
FormulaC18H32O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.868364-06-1
Synonyms9,10-Epoxyoctadecenoic acid
SMILESOC(CCCCCCCC1C(O1)C/C=C\CCCCC)=O
Biological Activity
Description9,10-EpOME (9,10-Epoxyoctadecenoic acid) is a cytochrome P450-derived metabolite of linoleic acid. It is known to induce oxidative stress by activating the NF-κB and AP-1 transcription factors and facilitates the chemotaxis of human neutrophils. Additionally, 9,10-EpOME has been shown to induce mechanical and thermal pain in wild-type mice via the PKA pathway. This compound is useful for investigating mechanisms of inflammation and pain in research settings.
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