Product Data Sheet
Palifosfamide tromethamine
Catalog No. A37310
Palifosfamide tromethamine is a synthetic alkylating agent that targets DNA, exhibiting potent antineoplastic activity. As the stabilized active metabolite of ifosfamide, it irreversibly alkylates and crosslinks DNA at GC base pairs, leading to inhibition of DNA replication and subsequent cell death. Palifosfamide tromethamine offers a reduced toxicity profile compared to its parent compound, making it a valuable tool for cancer research and therapeutic applications.
Chemical Information
| Catalog Num | A37310 |
|---|---|
| M. Wt | 342.16 |
| Formula | C8H22Cl2N3O5P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1070409-31-2 |
| Synonyms | Isophosphoramide mustard tromethamine; IPM tromethamine; ZIO-201 tromethamine |
| SMILES | O=P(NCCCl)(NCCCl)O.NC(CO)(CO)CO |
Biological Activity
| Description | Palifosfamide tromethamine is a synthetic alkylating agent that targets DNA, exhibiting potent antineoplastic activity. As the stabilized active metabolite of ifosfamide, it irreversibly alkylates and crosslinks DNA at GC base pairs, leading to inhibition of DNA replication and subsequent cell death. Palifosfamide tromethamine offers a reduced toxicity profile compared to its parent compound, making it a valuable tool for cancer research and therapeutic applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
