Product Data Sheet
HSP90-IN-32
Catalog No. A37583
HSP90-IN-32 is a selective inhibitor of the C-terminal domain of heat shock protein 90 (Hsp90). It exhibits significant anti-proliferative effects in various melanoma cell lines, including SKMel173, SKMel103, SKMel19, and A375, with IC50 values of 1.01 μM, 0.782 μM, 0.607 μM, and 1.413 μM, respectively. This compound holds potential for research focused on developing novel anti-cancer therapeutics targeting Hsp90.
Chemical Information
| Catalog Num | A37583 |
|---|---|
| M. Wt | 528.68 |
| Formula | C33H40N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2169279-38-1 |
| Synonyms | |
| SMILES | COC1=C(C2=CC(OC)=CC=C2)C=C(C=C1)C(N[C@H]3CC[C@H](C4=CC=C(C=C4)OC5CCN(CC5)C)CC3)=O |
Biological Activity
| Description | HSP90-IN-32 is a selective inhibitor of the C-terminal domain of heat shock protein 90 (Hsp90). It exhibits significant anti-proliferative effects in various melanoma cell lines, including SKMel173, SKMel103, SKMel19, and A375, with IC50 values of 1.01 μM, 0.782 μM, 0.607 μM, and 1.413 μM, respectively. This compound holds potential for research focused on developing novel anti-cancer therapeutics targeting Hsp90. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
