Product Data Sheet
HSP90-IN-12
Catalog No. A37613
HSP90-IN-12 is a potent inhibitor of Heat Shock Protein 90 (HSP90), a chaperone protein essential for protein folding and stability. This compound exhibits significant anti-proliferative effects across various cancer cell lines, making it a valuable tool in cancer research. HSP90-IN-12 disrupts the regulation of HSP90-related proteins and effectively inhibits the HSP90-mediated refolding of luciferase in vitro, highlighting its potential for studying HSP90 dynamics and therapeutic applications in oncology.
Chemical Information
| Catalog Num | A37613 |
|---|---|
| M. Wt | 400.55 |
| Formula | C25H36O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2408643-60-5 |
| Synonyms | |
| SMILES | C/C(C)=C\CC[C@@]1(/C=C/[C@H]([C@@]2(O[C@@H]2CCC(C(C1)=O)=C)C)OC(/C=C(C)/C)=O)C |
Biological Activity
| Description | HSP90-IN-12 is a potent inhibitor of Heat Shock Protein 90 (HSP90), a chaperone protein essential for protein folding and stability. This compound exhibits significant anti-proliferative effects across various cancer cell lines, making it a valuable tool in cancer research. HSP90-IN-12 disrupts the regulation of HSP90-related proteins and effectively inhibits the HSP90-mediated refolding of luciferase in vitro, highlighting its potential for studying HSP90 dynamics and therapeutic applications in oncology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
