Product Data Sheet
DHICA
Catalog No. A37712
DHICA is a GPR35 agonist that acts as both an eumelanin building block and a melanin synthesis intermediate. It activates GPR35, leading to dynamic mass redistribution and β-arrestin translocation. Additionally, DHICA promotes single-strand breaks in plasmid DNA and enhances the activity and expression levels of superoxide dismutase (SOD) and catalase. This compound is relevant for research applications in skin cancer and colon cancer studies.
Chemical Information
| Catalog Num | A37712 |
|---|---|
| M. Wt | 193.16 |
| Formula | C9H7NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 4790-08-3 |
| Synonyms | 5,6-Dihydroxyindole-2-carboxylic acid |
| SMILES | OC(C1=CC2=C(C=C(C(O)=C2)O)N1)=O |
Biological Activity
| Description | DHICA is a GPR35 agonist that acts as both an eumelanin building block and a melanin synthesis intermediate. It activates GPR35, leading to dynamic mass redistribution and β-arrestin translocation. Additionally, DHICA promotes single-strand breaks in plasmid DNA and enhances the activity and expression levels of superoxide dismutase (SOD) and catalase. This compound is relevant for research applications in skin cancer and colon cancer studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
