Product Data Sheet
Rifalazil
Catalog No. A37740
Rifalazil, a rifamycin derivative, targets bacterial DNA-dependent RNA polymerase, specifically inhibiting the β-subunit to disrupt RNA synthesis and induce bacterial cell death. This antibiotic demonstrates exceptional potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, Chlamydia pneumoniae, and Chlamydia trachomatis, with MIC values ranging from 0.00025 to 0.0025 μg/ml. Rifalazil shows promising potential for applications in treating Chlamydia infections, Clostridium difficile-associated diarrhea (CDAD), and tuberculosis (TB).
Chemical Information
| Catalog Num | A37740 |
|---|---|
| M. Wt | 941.07 |
| Formula | C51H64N4O13 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 129791-92-0 |
| Synonyms | KRM-1648; ABI-1648 |
| SMILES | CC(C)CN(CC1)CCN1C2=CC(O3)=C(C(O)=C2)N=C(C3=C(NC(/C(C)=C\C=C\[C@@H]([C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@@H]([C@@H]([C@H](/C=C/O[C@@]4(C)O5)OC)C)OC(C)=O)C)=O)C6=O)C7=C6C(O)=C(C)C5=C7C4=O |
Biological Activity
| Description | Rifalazil, a rifamycin derivative, targets bacterial DNA-dependent RNA polymerase, specifically inhibiting the β-subunit to disrupt RNA synthesis and induce bacterial cell death. This antibiotic demonstrates exceptional potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, Chlamydia pneumoniae, and Chlamydia trachomatis, with MIC values ranging from 0.00025 to 0.0025 μg/ml. Rifalazil shows promising potential for applications in treating Chlamydia infections, Clostridium difficile-associated diarrhea (CDAD), and tuberculosis (TB). |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
