Product Data Sheet

3-Isomangostin

Catalog No. A37831

main product photo
3-Isomangostin is a potent inhibitor of the MutT homologue 1 (MTH1) with an IC50 value of 52 nM, impacting DNA and RNA synthesis. Derived from the shell of Garcinia mangostana L., it presents a valuable chemical tool for investigating anticancer mechanisms and developing novel therapeutic strategies against cancer. Its ability to inhibit MTH1 highlights its potential for applications in cancer research and drug discovery.
Chemical Information
Catalog NumA37831
M. Wt410.46
FormulaC24H26O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.19275-46-8
Synonyms
SMILESC/C(C)=C\CC1=C2C(OC3=C(C(O)=C4C(OC(C)(C)CC4)=C3)C2=O)=CC(O)=C1OC
Biological Activity
Description3-Isomangostin is a potent inhibitor of the MutT homologue 1 (MTH1) with an IC50 value of 52 nM, impacting DNA and RNA synthesis. Derived from the shell of Garcinia mangostana L., it presents a valuable chemical tool for investigating anticancer mechanisms and developing novel therapeutic strategies against cancer. Its ability to inhibit MTH1 highlights its potential for applications in cancer research and drug discovery.
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