Product Data Sheet

Pefloxacin

Catalog No. A37907

main product photo
Pefloxacin is a broad-spectrum antibiotic that targets DNA gyrase, effectively inhibiting DNA replication. It exhibits significant antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis, with MIC90 values of 0.12, 4, and 16 mg/L, respectively. In addition to its antibacterial properties, Pefloxacin has demonstrated efficacy in reducing Plasmodium yoelii infections and may enhance UVA-induced edema and immunosuppression. This compound is suitable for various infection-related research applications.
Chemical Information
Catalog NumA37907
M. Wt333.36
FormulaC17H20FN3O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.70458-92-3
SynonymsPefloxacinium
SMILESO=C(C1=CN(CC)C2=C(C=C(F)C(N3CCN(C)CC3)=C2)C1=O)O
Biological Activity
DescriptionPefloxacin is a broad-spectrum antibiotic that targets DNA gyrase, effectively inhibiting DNA replication. It exhibits significant antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis, with MIC90 values of 0.12, 4, and 16 mg/L, respectively. In addition to its antibacterial properties, Pefloxacin has demonstrated efficacy in reducing Plasmodium yoelii infections and may enhance UVA-induced edema and immunosuppression. This compound is suitable for various infection-related research applications.
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