Product Data Sheet
8-NH2-ATP
Catalog No. A38091
8-NH2-ATP is an inhibitor of poly (ADP-ribose) polymerase (PARP), acting as a critical tool in research on cell apoptosis. This compound is derived from 8-NH2-Ado and exhibits potent effects by inducing apoptotic cleavage of PARP, making it useful for studying mechanisms of cell death, DNA repair, and cancer therapeutics. Its applications extend to exploring PARP's role in various biological pathways and assessing the therapeutic potential of PARP inhibition in disease models.
Chemical Information
| Catalog Num | A38091 |
|---|---|
| M. Wt | 522.20 |
| Formula | C10H17N6O13P3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 35874-49-8 |
| Synonyms | 8-Aminoadenosine-5'-O-triphosphate |
| SMILES | NC(N([C@]([C@@H]([C@@H]1O)O)([H])O[C@@H]1CO[P](O[P](O[P](O)(O)=O)(O)=O)(O)=O)C2=NC=N3)=NC2=C3N |
Biological Activity
| Description | 8-NH2-ATP is an inhibitor of poly (ADP-ribose) polymerase (PARP), acting as a critical tool in research on cell apoptosis. This compound is derived from 8-NH2-Ado and exhibits potent effects by inducing apoptotic cleavage of PARP, making it useful for studying mechanisms of cell death, DNA repair, and cancer therapeutics. Its applications extend to exploring PARP's role in various biological pathways and assessing the therapeutic potential of PARP inhibition in disease models. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
