Product Data Sheet

3'-Fluorothymidine-5'-triphosphate tetrasodium

Catalog No. A38121

main product photo
3'-Fluorothymidine-5'-triphosphate tetrasodium is a competitive inhibitor of T4 DNA polymerase, functioning as an analog of dTTP. By inhibiting T4 DNA polymerases, including wild-type, L98, and CB121 variants, it effectively disrupts DNA synthesis processes. This compound is valuable for research applications involving DNA replication studies and exploration of polymerase inhibition mechanisms.
Chemical Information
Catalog NumA38121
M. Wt572.09
FormulaC10H12FN2Na4O13P3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1443116-39-9
Synonyms3'-FdTTP tetrasodium
SMILESO=P(O[Na])(O[Na])OP(OP(OC[C@@H]1[C@@H](F)C[C@H](N(C=C(C(N2)=O)C)C2=O)O1)(O[Na])=O)(O[Na])=O
Biological Activity
Description3'-Fluorothymidine-5'-triphosphate tetrasodium is a competitive inhibitor of T4 DNA polymerase, functioning as an analog of dTTP. By inhibiting T4 DNA polymerases, including wild-type, L98, and CB121 variants, it effectively disrupts DNA synthesis processes. This compound is valuable for research applications involving DNA replication studies and exploration of polymerase inhibition mechanisms.
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SHIPPING AND STORAGE
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