Product Data Sheet

Dasabuvir sodium

Catalog No. A38134

main product photo
Dasabuvir sodium is a non-nucleoside inhibitor of hepatitis C virus (HCV) polymerase, specifically targeting the RNA-dependent RNA polymerase encoded by the HCV NS5B gene. It demonstrates potent antiviral activity against HCV genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC50 values of 7.7 nM and 1.8 nM, respectively. Dasabuvir sodium is primarily utilized in research focused on HCV replication and the development of antiviral therapies.
Chemical Information
Catalog NumA38134
M. Wt516.56
FormulaC26H27N3NaO5S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1132940-11-4
SynonymsABT-333 sodium
SMILESO=C1C=CN(C2=CC(C(C)(C)C)=C(OC)C(C3=CC=C4C=C(NS(=O)(C)=O)C=CC4=C3)=C2)C(N1)=O.[Na]
Biological Activity
DescriptionDasabuvir sodium is a non-nucleoside inhibitor of hepatitis C virus (HCV) polymerase, specifically targeting the RNA-dependent RNA polymerase encoded by the HCV NS5B gene. It demonstrates potent antiviral activity against HCV genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC50 values of 7.7 nM and 1.8 nM, respectively. Dasabuvir sodium is primarily utilized in research focused on HCV replication and the development of antiviral therapies.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.