Product Data Sheet

Ibezapolstat hydrochloride

Catalog No. A38276

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Ibezapolstat hydrochloride is a novel, orally active inhibitor of DNA polymerase IIIC (pol IIIC) with a Ki of 0.325 μM specific to the enzyme from Clostridium difficile. This compound exhibits antibiotic activity and is primarily utilized in research focused on Clostridium difficile infections (CDI). Its unique mechanism makes it a valuable tool for studying CDI and developing potential therapeutic strategies.
Chemical Information
Catalog NumA38276
M. Wt459.76
FormulaC18H21Cl3N6O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1275582-98-3
SynonymsACX-362E hydrochloride; GLS-362E hydrochloride
SMILESO=C1N=C(NCC2=CC=C(C(Cl)=C2)Cl)NC3=C1N(CCN4CCOCC4)C=N3.Cl
Biological Activity
DescriptionIbezapolstat hydrochloride is a novel, orally active inhibitor of DNA polymerase IIIC (pol IIIC) with a Ki of 0.325 μM specific to the enzyme from Clostridium difficile. This compound exhibits antibiotic activity and is primarily utilized in research focused on Clostridium difficile infections (CDI). Its unique mechanism makes it a valuable tool for studying CDI and developing potential therapeutic strategies.
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SHIPPING AND STORAGE
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