Product Data Sheet

NSC 660028

Catalog No. A38298

main product photo
NSC 660028 is a potent inhibitor of DNA topoisomerase II, exhibiting an ID50 of 50 μM. This compound disrupts DNA topoisomerase II activity, leading to the induction of protein-linked DNA breaks. NSC 660028 is primarily utilized in cancer research to explore mechanisms of tumor cell proliferation and resistance.
Chemical Information
Catalog NumA38298
M. Wt461.51
FormulaC27H27NO6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.153230-81-0
Synonyms
SMILESN([C@@H]1C=2C([C@H]([C@@]3([C@@]1(COC3)[H])[H])C4=CC(OC)=C(O)C(OC)=C4)=CC5=C(C2)OCO5)C6=CC=CC=C6
Biological Activity
DescriptionNSC 660028 is a potent inhibitor of DNA topoisomerase II, exhibiting an ID50 of 50 μM. This compound disrupts DNA topoisomerase II activity, leading to the induction of protein-linked DNA breaks. NSC 660028 is primarily utilized in cancer research to explore mechanisms of tumor cell proliferation and resistance.
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