Product Data Sheet

DHODH-IN-24

Catalog No. A38539

main product photo
DHODH-IN-24 is a potent inhibitor of human dihydroorotate dehydrogenase (DHODH) with an IC50 value of 91 nM. This compound effectively impairs the proliferation of rapidly dividing cells by hindering pyrimidine synthesis. DHODH-IN-24 is an important tool for investigating the role of DHODH in various biological processes and may have applications in the research of autoimmune diseases and cancer therapy.
Chemical Information
Catalog NumA38539
M. Wt394.51
FormulaC26H26N4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.418775-30-1
Synonyms
SMILESCN(CCN(C)/N=C/C1=CC=CC2=C1C=CC=C2)/N=C/C3=CC=CC4=C3C=CC=C4
Biological Activity
DescriptionDHODH-IN-24 is a potent inhibitor of human dihydroorotate dehydrogenase (DHODH) with an IC50 value of 91 nM. This compound effectively impairs the proliferation of rapidly dividing cells by hindering pyrimidine synthesis. DHODH-IN-24 is an important tool for investigating the role of DHODH in various biological processes and may have applications in the research of autoimmune diseases and cancer therapy.
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