Product Data Sheet

A-65282

Catalog No. A38576

main product photo
A-65282 is an antibacterial agent that inhibits P4 DNA unknotting, exhibiting an IC50 value of 8 µg/mL. This compound induces DNA breakage through the action of calf thymus topoisomerase II, making it a valuable tool for studying DNA replication and repair mechanisms. Its targeted enzymatic disruption highlights its potential in antibacterial research contexts.
Chemical Information
Catalog NumA38576
M. Wt378.40
FormulaC17H16F2N4O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.135906-72-8
Synonyms
SMILESO=C1NSC(N(C2CC2)C3=C4C=C(F)C(N5CC(N)CC5)=C3F)=C1C4=O
Biological Activity
DescriptionA-65282 is an antibacterial agent that inhibits P4 DNA unknotting, exhibiting an IC50 value of 8 µg/mL. This compound induces DNA breakage through the action of calf thymus topoisomerase II, making it a valuable tool for studying DNA replication and repair mechanisms. Its targeted enzymatic disruption highlights its potential in antibacterial research contexts.
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