Eponemycin
Catalog No. A38579

Eponemycin is an antibiotic with significant antitumor properties, targeting cancer cell proliferation. It demonstrates potent cytotoxicity against various cancer cell lines including B16-F10, L1210, P388, and HCT-116, with IC50 values of 0.0017, 0.01, 0.031, and 0.0097 µg/mL, respectively. Additionally, Eponemycin effectively inhibits DNA synthesis in the B16-F10 cell line, exhibiting an IC50 of 0.1 µg/mL, thereby demonstrating its utility in cancer research applications focused on DNA replication and cell viability.
Chemical Information
| Catalog Num | A38579 |
|---|---|
| M. Wt | 398.49 |
| Formula | C20H34N2O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 126509-46-4 |
| Synonyms | |
| SMILES | CC(C)CCCCC(N[C@@H](CO)C(N[C@@H](CC(C)=C)C([C@]1(CO1)CO)=O)=O)=O |
Biological Activity
| Description | Eponemycin is an antibiotic with significant antitumor properties, targeting cancer cell proliferation. It demonstrates potent cytotoxicity against various cancer cell lines including B16-F10, L1210, P388, and HCT-116, with IC50 values of 0.0017, 0.01, 0.031, and 0.0097 µg/mL, respectively. Additionally, Eponemycin effectively inhibits DNA synthesis in the B16-F10 cell line, exhibiting an IC50 of 0.1 µg/mL, thereby demonstrating its utility in cancer research applications focused on DNA replication and cell viability. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


