Product Data Sheet
3'-NH-Tr-2',3'-DMF-ddA- 5'-CE-Phosphoramidite
Catalog No. A38585
3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite is a nucleoside antimetabolite that serves as an adenine nucleotide monomer precursor in the solid-phase synthesis of oligonucleotides. This compound features trityl (Tr), cyanoethyl (CE), and dimethylformamidine (DMF) protecting groups, making it ideal for producing modified oligonucleotides, including those with specific DNA chain end modifications. Applications include oligonucleotide synthesis, probe design, and chain-termination sequencing, where it plays a crucial role in enhancing the specificity and performance of nucleic acid-based assays.
Chemical Information
| Catalog Num | A38585 |
|---|---|
| M. Wt | 747.87 |
| Formula | C41H50N9O3P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1644649-86-4 |
| Synonyms | |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)OC[C@H]1O[C@@H](N2C3=NC=NC(/N=C/N(C)C)=C3N=C2)C[C@@H]1NC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6 |
Biological Activity
| Description | 3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite is a nucleoside antimetabolite that serves as an adenine nucleotide monomer precursor in the solid-phase synthesis of oligonucleotides. This compound features trityl (Tr), cyanoethyl (CE), and dimethylformamidine (DMF) protecting groups, making it ideal for producing modified oligonucleotides, including those with specific DNA chain end modifications. Applications include oligonucleotide synthesis, probe design, and chain-termination sequencing, where it plays a crucial role in enhancing the specificity and performance of nucleic acid-based assays. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
