Product Data Sheet
Aphidicolin 17-acetate
Catalog No. A38669
Aphidicolin 17-acetate is a selective inhibitor of eukaryotic DNA polymerase α. This compound significantly impairs in vivo DNA synthesis in model systems such as sea urchin embryos and HeLa cells while demonstrating no effect on RNA and protein synthesis. Its specificity for DNA polymerase α, without inhibition of polymerases β and γ, makes Aphidicolin 17-acetate a valuable tool for studying DNA replication processes and cellular responses to DNA damage.
Chemical Information
| Catalog Num | A38669 |
|---|---|
| M. Wt | 380.52 |
| Formula | C22H36O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 51103-57-2 |
| Synonyms | Aphidicolin 17-monoacetate |
| SMILES | O[C@]1(COC(C)=O)CC[C@@]23[C@@]([C@@]4([H])CC[C@@]2([H])C[C@@H]1C3)(C)CC[C@@H](O)[C@@]4(C)CO |
Biological Activity
| Description | Aphidicolin 17-acetate is a selective inhibitor of eukaryotic DNA polymerase α. This compound significantly impairs in vivo DNA synthesis in model systems such as sea urchin embryos and HeLa cells while demonstrating no effect on RNA and protein synthesis. Its specificity for DNA polymerase α, without inhibition of polymerases β and γ, makes Aphidicolin 17-acetate a valuable tool for studying DNA replication processes and cellular responses to DNA damage. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
