Product Data Sheet
OB-24
Catalog No. A38848
OB-24 is a selective small-molecule inhibitor of heme oxygenase-1 (HO-1), demonstrating an IC50 of 1.9 μM for HO-1 with minimal effect on HO-2 (IC50 > 100 μM). This compound exhibits significant anti-tumor and anti-metastatic activities, making it valuable for research applications in various cancer models, including prostate cancer, melanoma, ovarian carcinoma, and lung metastasis. OB-24 may serve as an essential tool for understanding HO-1's role in tumor progression and metastasis.
Chemical Information
| Catalog Num | A38848 |
|---|---|
| M. Wt | 373.67 |
| Formula | C15H18BrClN2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 939825-12-4 |
| Synonyms | |
| SMILES | BrC1=CC=C(CCC2(CN3C=CN=C3)OCCO2)C=C1.Cl |
Biological Activity
| Description | OB-24 is a selective small-molecule inhibitor of heme oxygenase-1 (HO-1), demonstrating an IC50 of 1.9 μM for HO-1 with minimal effect on HO-2 (IC50 > 100 μM). This compound exhibits significant anti-tumor and anti-metastatic activities, making it valuable for research applications in various cancer models, including prostate cancer, melanoma, ovarian carcinoma, and lung metastasis. OB-24 may serve as an essential tool for understanding HO-1's role in tumor progression and metastasis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
