Product Data Sheet
Oleocanthal
Catalog No. A38967
Oleocanthal is a phenolic seciridoid compound primarily known for its inhibition of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). This agent exhibits significant anti-inflammatory and neuroprotective properties, along with reducing reactive oxygen species (ROS) and nitric oxide (NO) while upregulating Nrf-2 and HO-1. Oleocanthal also has demonstrated efficacy in reducing amyloid-beta (Aβ) deposition and shows anticancer activity across various cancer types, including colon, breast, liver, and melanoma. Additionally, it displays anti-Leishmania activity against L. major, making it a valuable reagent for Alzheimer’s disease and cancer research.
Chemical Information
| Catalog Num | A38967 |
|---|---|
| M. Wt | 304.34 |
| Formula | C17H20O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 289030-99-5 |
| Synonyms | |
| SMILES | C/C=C([C@H](CC(OCCC1=CC=C(C=C1)O)=O)CC=O)/C=O |
Biological Activity
| Description | Oleocanthal is a phenolic seciridoid compound primarily known for its inhibition of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). This agent exhibits significant anti-inflammatory and neuroprotective properties, along with reducing reactive oxygen species (ROS) and nitric oxide (NO) while upregulating Nrf-2 and HO-1. Oleocanthal also has demonstrated efficacy in reducing amyloid-beta (Aβ) deposition and shows anticancer activity across various cancer types, including colon, breast, liver, and melanoma. Additionally, it displays anti-Leishmania activity against L. major, making it a valuable reagent for Alzheimer’s disease and cancer research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
