Product Data Sheet
Leteprinim potassium
Catalog No. A39012
Leteprinim potassium (AIT-082) is a purine analog that functions as a neuroprotective agent. This compound enhances cognitive function by promoting the production of brain-derived neurotrophic factor (BDNF) mRNA in response to spinal cord injuries, and nerve growth factor (NGF) mRNA in the basal forebrain. Additionally, Leteprinim potassium mitigates glutamate-induced toxicity in cultured hippocampal neurons and elevates the mRNA levels of heme oxygenase 1 and 2, contributing to cellular defense against reactive oxygen species. Its applications extend to research on neuroprotection and cognitive enhancement strategies.
Chemical Information
| Catalog Num | A39012 |
|---|---|
| M. Wt | 365.39 |
| Formula | C15H12KN5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 192564-13-9 |
| Synonyms | AIT-082 |
| SMILES | O=C(C1=CC=C(C=C1)NC(CCN2C=NC3=C2N=CNC3=O)=O)O[K] |
Biological Activity
| Description | Leteprinim potassium (AIT-082) is a purine analog that functions as a neuroprotective agent. This compound enhances cognitive function by promoting the production of brain-derived neurotrophic factor (BDNF) mRNA in response to spinal cord injuries, and nerve growth factor (NGF) mRNA in the basal forebrain. Additionally, Leteprinim potassium mitigates glutamate-induced toxicity in cultured hippocampal neurons and elevates the mRNA levels of heme oxygenase 1 and 2, contributing to cellular defense against reactive oxygen species. Its applications extend to research on neuroprotection and cognitive enhancement strategies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
