Product Data Sheet

Benz-AP

Catalog No. A39076

main product photo
Benz-AP is a potent photosensitizer that generates singlet oxygen, exhibiting a negative correlation with human carboxylesterase 2 (hCES2) activity. This compound demonstrates enhanced photocytotoxicity in cancer cells, particularly in environments with low hCES2 levels. Upon two-photon excitation (TPE), Benz-AP produces reactive oxygen species (ROS), effectively inducing cell death in cancer cells and tumor spheroids, making it a valuable tool for cancer research applications.
Chemical Information
Catalog NumA39076
M. Wt299.32
FormulaC20H13NO2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2416220-53-4
Synonyms
SMILESO=C(NC1=C2C=CC=C3C(C=CC(C=C1)=C32)=O)C4=CC=CC=C4
Biological Activity
DescriptionBenz-AP is a potent photosensitizer that generates singlet oxygen, exhibiting a negative correlation with human carboxylesterase 2 (hCES2) activity. This compound demonstrates enhanced photocytotoxicity in cancer cells, particularly in environments with low hCES2 levels. Upon two-photon excitation (TPE), Benz-AP produces reactive oxygen species (ROS), effectively inducing cell death in cancer cells and tumor spheroids, making it a valuable tool for cancer research applications.
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SHIPPING AND STORAGE
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