Product Data Sheet
Brevicidine
Catalog No. A39169
Brevicidine is an antimicrobial peptide that demonstrates selective bactericidal activity against Gram-negative pathogens. It functions by binding to lipopolysaccharide (LPS) on the bacterial cell membrane, leading to pore formation and subsequent disruption of bacterial morphology. This results in the dissipation of the proton motive force, outer membrane damage, inhibition of ATP biosynthesis, and accumulation of reactive oxygen species within bacterial cells. Additionally, Brevicidine acts as a sensitizer, exhibiting synergistic effects when combined with various conventional antibiotics, making it valuable for research in antimicrobial resistance and antibiotic enhancement studies.
Chemical Information
| Catalog Num | A39169 |
|---|---|
| M. Wt | 1519.74 |
| Formula | C74H106N18O17 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2676889-05-5 |
| Synonyms | |
| SMILES |
Biological Activity
| Description | Brevicidine is an antimicrobial peptide that demonstrates selective bactericidal activity against Gram-negative pathogens. It functions by binding to lipopolysaccharide (LPS) on the bacterial cell membrane, leading to pore formation and subsequent disruption of bacterial morphology. This results in the dissipation of the proton motive force, outer membrane damage, inhibition of ATP biosynthesis, and accumulation of reactive oxygen species within bacterial cells. Additionally, Brevicidine acts as a sensitizer, exhibiting synergistic effects when combined with various conventional antibiotics, making it valuable for research in antimicrobial resistance and antibiotic enhancement studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
