Product Data Sheet
Pegtarazimod
Catalog No. A39188
Pegtarazimod is a dual-target anti-inflammatory peptide that regulates both the complement system and neutrophil-associated inflammatory pathways. It demonstrates significant biological activity by reducing reactive oxygen species (ROS) production and lowering neutrophil elastase levels in vivo, thereby mitigating inflammatory responses. Pegtarazimod has shown improved survival rates in multiple in vivo models of acute graft-versus-host disease (aGVHD) and exhibits efficacy against herpes simplex virus type 1 infections by inhibiting the activation of the C1 complex. This reagent is applicable in research focused on aGVHD, acute pulmonary diseases, and skin infections caused by herpes simplex virus type 1.
Chemical Information
| Catalog Num | A39188 |
|---|---|
| M. Wt | 2771.32 |
| Formula | C122H224N20O46S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2056232-82-5 |
| Synonyms | RLS-0071 |
| SMILES | CC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O)N |
Biological Activity
| Description | Pegtarazimod is a dual-target anti-inflammatory peptide that regulates both the complement system and neutrophil-associated inflammatory pathways. It demonstrates significant biological activity by reducing reactive oxygen species (ROS) production and lowering neutrophil elastase levels in vivo, thereby mitigating inflammatory responses. Pegtarazimod has shown improved survival rates in multiple in vivo models of acute graft-versus-host disease (aGVHD) and exhibits efficacy against herpes simplex virus type 1 infections by inhibiting the activation of the C1 complex. This reagent is applicable in research focused on aGVHD, acute pulmonary diseases, and skin infections caused by herpes simplex virus type 1. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
