Product Data Sheet
PKHB1
Catalog No. A39225
PKHB1 is a thrombospondin-1 peptide mimic that exerts antitumor effects primarily through mitochondrial dysfunction. It promotes the production of reactive oxygen species (ROS), triggers intracellular calcium accumulation, and activates calcium-dependent apoptotic pathways in breast cancer cells. Additionally, PKHB1 facilitates immune system activation by inducing immunogenic cell death, making it a valuable tool for research into cancer therapeutics and immunology.
Chemical Information
| Catalog Num | A39225 |
|---|---|
| M. Wt | 1384.73 |
| Formula | C68H105N17O12S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1505523-99-8 |
| Synonyms | txCD47 |
| SMILES | C([C@@H](C(N[C@H](C(N[C@H](CCCCN)C(O)=O)=O)CCCCN)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](CCCCN)N)=O)CCCNC(=N)N)=O)=O)=O)C(C)C)=O)[C@H](C)C)=O)CCSC)=O)C=3C=4C(NC3)=CC=CC4 |
Biological Activity
| Description | PKHB1 is a thrombospondin-1 peptide mimic that exerts antitumor effects primarily through mitochondrial dysfunction. It promotes the production of reactive oxygen species (ROS), triggers intracellular calcium accumulation, and activates calcium-dependent apoptotic pathways in breast cancer cells. Additionally, PKHB1 facilitates immune system activation by inducing immunogenic cell death, making it a valuable tool for research into cancer therapeutics and immunology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
