Product Data Sheet

Antitumor agent-68

Catalog No. A39244

main product photo
Antitumor agent-68 is a potent tubulin inhibitor that demonstrates significant anticancer activity, with IC50 values of 3.6 μM and 3.8 μM against HeLa and MCF-7 cancer cell lines, respectively. This compound exhibits strong reactive oxygen species (ROS) and DPPH radical scavenging activity in a dose-dependent manner, making it relevant for oxidative stress research. Antitumor agent-68 also features an alkyne group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions, facilitating advancements in chemical biology applications.
Chemical Information
Catalog NumA39244
M. Wt261.27
FormulaC17H11NO2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2566497-96-7
Synonyms
SMILESO=C(OC1=CC2=C(NC=C2)C=C1)C#CC3=CC=CC=C3
Biological Activity
DescriptionAntitumor agent-68 is a potent tubulin inhibitor that demonstrates significant anticancer activity, with IC50 values of 3.6 μM and 3.8 μM against HeLa and MCF-7 cancer cell lines, respectively. This compound exhibits strong reactive oxygen species (ROS) and DPPH radical scavenging activity in a dose-dependent manner, making it relevant for oxidative stress research. Antitumor agent-68 also features an alkyne group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions, facilitating advancements in chemical biology applications.
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