Product Data Sheet
Artocarpin
Catalog No. A39247
Artocarpin is a potent apoptosis inducer that targets various signaling molecules, including NF-κB, Erk1/2, p38 MAPK, and Akt kinases. It stimulates the production of reactive oxygen species (ROS) and activates both p53-dependent and independent apoptotic pathways, resulting in G1-phase cell cycle arrest and autophagic cell death. Artocarpin displays significant cytotoxic and bactericidal effects against cancer cells, reduces bacterial burden, and possesses anti-inflammatory, analgesic, and anti-angiogenic properties, making it valuable for cancer and inflammatory research applications.
Chemical Information
| Catalog Num | A39247 |
|---|---|
| M. Wt | 436.50 |
| Formula | C26H28O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 7608-44-8 |
| Synonyms | |
| SMILES | C/C(C)=C\CC1=C(C2=C(C=C(O)C=C2)O)OC3=CC(OC)=C(/C=C/C(C)C)C(O)=C3C1=O |
Biological Activity
| Description | Artocarpin is a potent apoptosis inducer that targets various signaling molecules, including NF-κB, Erk1/2, p38 MAPK, and Akt kinases. It stimulates the production of reactive oxygen species (ROS) and activates both p53-dependent and independent apoptotic pathways, resulting in G1-phase cell cycle arrest and autophagic cell death. Artocarpin displays significant cytotoxic and bactericidal effects against cancer cells, reduces bacterial burden, and possesses anti-inflammatory, analgesic, and anti-angiogenic properties, making it valuable for cancer and inflammatory research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
