Product Data Sheet
N1-Acetyl-5-methoxykynuramine hydrochloride
Catalog No. A39324
N1-Acetyl-5-methoxykynuramine hydrochloride is a potent inhibitor of prostaglandin E2 (PGE2) production, acting as an active metabolite of melatonin. This compound effectively scavenges reactive oxygen species and suppresses COX-2 expression in RAW 264.7 macrophages in a dose- and time-dependent manner. Additionally, in a mouse model of Parkinson's disease induced by MPTP, it diminishes lipid peroxidation in key brain regions. N1-Acetyl-5-methoxykynuramine hydrochloride is relevant for research focused on metabolic and neurological disorders.
Chemical Information
| Catalog Num | A39324 |
|---|---|
| M. Wt | 272.73 |
| Formula | C12H17ClN2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1215711-91-3 |
| Synonyms | AMK hydrochloride |
| SMILES | O=C(C)NCCC(C1=CC(OC)=CC=C1N)=O.Cl |
Biological Activity
| Description | N1-Acetyl-5-methoxykynuramine hydrochloride is a potent inhibitor of prostaglandin E2 (PGE2) production, acting as an active metabolite of melatonin. This compound effectively scavenges reactive oxygen species and suppresses COX-2 expression in RAW 264.7 macrophages in a dose- and time-dependent manner. Additionally, in a mouse model of Parkinson's disease induced by MPTP, it diminishes lipid peroxidation in key brain regions. N1-Acetyl-5-methoxykynuramine hydrochloride is relevant for research focused on metabolic and neurological disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
