Product Data Sheet
U0126
Catalog No. A39329
U0126 is a selective inhibitor of MEK1 and MEK2, functioning through a non-ATP competitive mechanism. It demonstrates potent biological activity with IC50 values of 72 nM and 58 nM for MEK1 and MEK2, respectively. U0126 is utilized in research to investigate autophagy and mitophagy processes, providing insights into cellular signaling pathways and potential therapeutic targets in cancer and other diseases.
Chemical Information
| Catalog Num | A39329 |
|---|---|
| M. Wt | 380.49 |
| Formula | C18H16N6S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 109511-58-2 |
| Synonyms | |
| SMILES | NC1=CC=CC=C1S/C(N)=C(C#N)/C(C#N)=C(N)/SC2=CC=CC=C2N |
Biological Activity
| Description | U0126 is a selective inhibitor of MEK1 and MEK2, functioning through a non-ATP competitive mechanism. It demonstrates potent biological activity with IC50 values of 72 nM and 58 nM for MEK1 and MEK2, respectively. U0126 is utilized in research to investigate autophagy and mitophagy processes, providing insights into cellular signaling pathways and potential therapeutic targets in cancer and other diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
