Meglutol
Catalog No. A39357

Meglutol is an endogenous metabolite that functions as a lipid-lowering agent by inhibiting HMG-CoA reductase, a key enzyme in cholesterol biosynthesis. It effectively reduces levels of cholesterol, triglycerides, serum β-lipoprotein, and phospholipids. Additionally, Meglutol is noted for inducing significant lipid oxidative damage in brain tissue, making it a valuable tool for research in cardiovascular and metabolic diseases.
Chemical Information
| Catalog Num | A39357 |
|---|---|
| M. Wt | 162.14 |
| Formula | C6H10O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 503-49-1 |
| Synonyms | Dicrotalic acid; 3-Hydroxy-3-methylglutaric acid |
| SMILES | O=C(O)CC(C)(O)CC(O)=O |
Biological Activity
| Description | Meglutol is an endogenous metabolite that functions as a lipid-lowering agent by inhibiting HMG-CoA reductase, a key enzyme in cholesterol biosynthesis. It effectively reduces levels of cholesterol, triglycerides, serum β-lipoprotein, and phospholipids. Additionally, Meglutol is noted for inducing significant lipid oxidative damage in brain tissue, making it a valuable tool for research in cardiovascular and metabolic diseases. |
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RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


