Product Data Sheet
MLCK inhibitor peptide 18
Catalog No. A39376
MLCK Inhibitor Peptide 18 is a selective inhibitor of myosin light chain kinase (MLCK) with an IC50 of 50 nM. This peptide demonstrates significant inhibition of MLCK activity while exhibiting minimal effects on Ca2+/calmodulin-dependent protein kinase II, requiring concentrations approximately 4000-fold higher for inhibition. This specificity makes it valuable for studying MLCK-related signaling pathways and cellular processes involving muscle contraction and cellular motility.
Chemical Information
| Catalog Num | A39376 |
|---|---|
| M. Wt | 1324.62 |
| Formula | C60H105N23O11 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 224579-74-2 |
| Synonyms | |
| SMILES | [C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCCN)=O)CCCCN)=O)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O |
Biological Activity
| Description | MLCK Inhibitor Peptide 18 is a selective inhibitor of myosin light chain kinase (MLCK) with an IC50 of 50 nM. This peptide demonstrates significant inhibition of MLCK activity while exhibiting minimal effects on Ca2+/calmodulin-dependent protein kinase II, requiring concentrations approximately 4000-fold higher for inhibition. This specificity makes it valuable for studying MLCK-related signaling pathways and cellular processes involving muscle contraction and cellular motility. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
