Product Data Sheet
YW3-56 hydrochloride
Catalog No. A39739
YW3-56 hydrochloride is a potent inhibitor of peptidylarginine deiminases (PADs). It is known to activate p53 target genes and modulate the ATF pathway, effectively blocking autophagic flux. Additionally, YW3-56 induces endoplasmic reticulum (ER) stress through the PERK-eIF2α-ATF4 signaling cascade while inhibiting the mTOR pathway. This compound has demonstrated potential in the treatment of triple-negative breast cancer, making it a valuable reagent for cancer research and therapeutic studies.
Chemical Information
| Catalog Num | A39739 |
|---|---|
| M. Wt | 530.49 |
| Formula | C27H33Cl2N5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2309756-20-3 |
| Synonyms | |
| SMILES | O=C(C1=CC=C2C=C(N(C)C)C=CC2=C1)N[C@H](C(NCC3=CC=CC=C3)=O)CCCNC(CCl)=N.Cl |
Biological Activity
| Description | YW3-56 hydrochloride is a potent inhibitor of peptidylarginine deiminases (PADs). It is known to activate p53 target genes and modulate the ATF pathway, effectively blocking autophagic flux. Additionally, YW3-56 induces endoplasmic reticulum (ER) stress through the PERK-eIF2α-ATF4 signaling cascade while inhibiting the mTOR pathway. This compound has demonstrated potential in the treatment of triple-negative breast cancer, making it a valuable reagent for cancer research and therapeutic studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
