Product Data Sheet
5-Azacytidine-15N4
Catalog No. A39745
5-Azacytidine-15N4 is a stable isotope-labeled version of 5-Azacytidine, featuring both 13C and 15N isotopes. As a nucleoside analogue of cytidine, 5-Azacytidine specifically inhibits DNA methylation by being incorporated into DNA, thereby covalently trapping DNA methyltransferases. This process contributes to the reversal of epigenetic modifications. Additionally, 5-Azacytidine has been shown to induce autophagy in cells, making it valuable for research in epigenetics and cellular metabolism.
Chemical Information
| Catalog Num | A39745 |
|---|---|
| M. Wt | 248.18 |
| Formula | C8H1215N4O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2139283-40-0 |
| Synonyms | Azacitidine-15N4; 5-AzaC-15N4; Ladakamycin-15N4 |
| SMILES | OC[C@@H]1[C@@H](O)[C@@H](O)[C@H]([15N](C=[15N]2)C([15N]=C2[15NH2])=O)O1 |
Biological Activity
| Description | 5-Azacytidine-15N4 is a stable isotope-labeled version of 5-Azacytidine, featuring both 13C and 15N isotopes. As a nucleoside analogue of cytidine, 5-Azacytidine specifically inhibits DNA methylation by being incorporated into DNA, thereby covalently trapping DNA methyltransferases. This process contributes to the reversal of epigenetic modifications. Additionally, 5-Azacytidine has been shown to induce autophagy in cells, making it valuable for research in epigenetics and cellular metabolism. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
