Product Data Sheet

Cathepsin K-IN-9

Catalog No. A39892

main product photo
Cathepsin K-IN-9 is a potent and selective inhibitor of Cathepsin K, exhibiting an IC50 of 6.2 nM. It demonstrates remarkable selectivity with IC50 values exceeding 10,000 nM for Cathepsins B, L, and S, providing over 1600-fold selectivity. With its excellent safety profile and metabolic stability, Cathepsin K-IN-9 is suitable for research applications in osteoporosis and other bone resorption-related studies.
Chemical Information
Catalog NumA39892
M. Wt575.75
FormulaC35H41N7O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2361420-28-0
Synonyms
SMILESCNC1=NC(C#N)=NC2=C1C=C(N2CC(C)(C)C)C(NCC3=CC=C(C=C3)C4=CC=C(C=C4)C5CCN(CC5)C6CC6)=O
Biological Activity
DescriptionCathepsin K-IN-9 is a potent and selective inhibitor of Cathepsin K, exhibiting an IC50 of 6.2 nM. It demonstrates remarkable selectivity with IC50 values exceeding 10,000 nM for Cathepsins B, L, and S, providing over 1600-fold selectivity. With its excellent safety profile and metabolic stability, Cathepsin K-IN-9 is suitable for research applications in osteoporosis and other bone resorption-related studies.
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