Product Data Sheet
Saroglitazar magnesium
Catalog No. A39943
Saroglitazar magnesium is a selective agonist of peroxisome proliferator-activated receptors PPARα and PPARγ, exhibiting high potency with EC50 values of 0.65 pM and 3 nM, respectively, in HepG2 cells. This compound plays a crucial role in lipid metabolism and glucose homeostasis, making it a valuable tool for research in metabolic disorders such as dyslipidemia and type 2 diabetes. Its dual activity on PPARα and PPARγ positions it as a significant candidate for exploring therapeutic strategies in metabolic disease models.
Chemical Information
| Catalog Num | A39943 |
|---|---|
| M. Wt | 901.42 |
| Formula | C50H56MgN2O8S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1639792-20-3 |
| Synonyms | |
| SMILES | CCO([Mg+2]1(O(CC)[C@H](C([O-]1)=O)CC2=CC=C(OCCN3C(C)=CC=C3C4=CC=C(SC)C=C4)C=C2)[O-]C5=O)[C@H]5CC6=CC=C(OCCN7C(C)=CC=C7C8=CC=C(SC)C=C8)C=C6 |
Biological Activity
| Description | Saroglitazar magnesium is a selective agonist of peroxisome proliferator-activated receptors PPARα and PPARγ, exhibiting high potency with EC50 values of 0.65 pM and 3 nM, respectively, in HepG2 cells. This compound plays a crucial role in lipid metabolism and glucose homeostasis, making it a valuable tool for research in metabolic disorders such as dyslipidemia and type 2 diabetes. Its dual activity on PPARα and PPARγ positions it as a significant candidate for exploring therapeutic strategies in metabolic disease models. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
