Product Data Sheet
SR 11023
Catalog No. A39984
SR 11023 is a potent orally active antagonist of PPARγ, exhibiting an IC50 value of 109 nM. This compound is significant in the study of metabolic disorders, particularly in diabetes research, where PPARγ modulation can impact insulin sensitivity and adipocyte differentiation. Researchers can utilize SR 11023 to investigate the therapeutic potential of targeting PPARγ in various metabolic pathways.
Chemical Information
| Catalog Num | A39984 |
|---|---|
| M. Wt | 508.65 |
| Formula | C33H36N2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1820602-13-8 |
| Synonyms | |
| SMILES | C[C@@H](C1=CC(C2CC2)=CC=C1)NC(C3=CC=C(C(C(C)=C4C)=C3)N4CC5=CC=C(C=C5)C(C)(C)C(O)=O)=O |
Biological Activity
| Description | SR 11023 is a potent orally active antagonist of PPARγ, exhibiting an IC50 value of 109 nM. This compound is significant in the study of metabolic disorders, particularly in diabetes research, where PPARγ modulation can impact insulin sensitivity and adipocyte differentiation. Researchers can utilize SR 11023 to investigate the therapeutic potential of targeting PPARγ in various metabolic pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
