Product Data Sheet
BAY-0069
Catalog No. A39989
BAY-0069 is a selective inverse agonist of PPARγ, exhibiting potent inhibition with IC50 values of 6.3 nM for human PPARγ and 24 nM for mouse PPARγ. This compound serves as a valuable tool for investigating the roles of PPARγ in cancer research, providing insights into its regulatory mechanisms in tumorigenesis and potential therapeutic strategies. Its high selectivity enhances its utility in experimental settings.
Chemical Information
| Catalog Num | A39989 |
|---|---|
| M. Wt | 466.28 |
| Formula | C22H16BrN3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 420826-65-9 |
| Synonyms | |
| SMILES | O=C(NC1=CC=C(OC(C2=CC=C(CC)C=C2)=N3)C3=C1)C4=CC([N+]([O-])=O)=CC=C4Br |
Biological Activity
| Description | BAY-0069 is a selective inverse agonist of PPARγ, exhibiting potent inhibition with IC50 values of 6.3 nM for human PPARγ and 24 nM for mouse PPARγ. This compound serves as a valuable tool for investigating the roles of PPARγ in cancer research, providing insights into its regulatory mechanisms in tumorigenesis and potential therapeutic strategies. Its high selectivity enhances its utility in experimental settings. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
