Product Data Sheet
PPARγ agonist 16
Catalog No. A40104
PPARγ Agonist 16 acts as a selective agonist for peroxisome proliferator-activated receptor gamma (PPARγ), demonstrating competitive binding to the ligand-binding domain (LBD) with an IC50 of 1790 nM. This compound is notable for its ability to inhibit ear swelling in murine models and shows promising anti-hyperglycemic effects in streptozotocin-induced diabetes models. PPARγ Agonist 16 is valuable for research applications focused on metabolic disorders and inflammation.
Chemical Information
| Catalog Num | A40104 |
|---|---|
| M. Wt | 432.29 |
| Formula | C19H14BrNO4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2218046-01-4 |
| Synonyms | |
| SMILES | BrC1=CC=C(C(CN2C(/C(SC2=O)=C/C3=C(OC)C=CC=C3)=O)=O)C=C1 |
Biological Activity
| Description | PPARγ Agonist 16 acts as a selective agonist for peroxisome proliferator-activated receptor gamma (PPARγ), demonstrating competitive binding to the ligand-binding domain (LBD) with an IC50 of 1790 nM. This compound is notable for its ability to inhibit ear swelling in murine models and shows promising anti-hyperglycemic effects in streptozotocin-induced diabetes models. PPARγ Agonist 16 is valuable for research applications focused on metabolic disorders and inflammation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
