Product Data Sheet

AMG131 benzenesulfonate

Catalog No. A40109

main product photo
AMG131 benzenesulfonate is a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist, classified as a non-thiazolidinedione (TZD) modulator. It binds to the PPARγ receptor, occupying a unique position in the binding pocket, which allows for distinct interactions compared to traditional TZDs. This compound has demonstrated potential in research pertaining to the treatment of type-2 diabetes mellitus, making it a valuable tool for investigating PPARγ-related metabolic pathways.
Chemical Information
Catalog NumA40109
M. Wt672.38
FormulaC27H18Cl4N2O6S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.849738-78-9
SynonymsINT131 benzenesulfonate
SMILESO=S(O)(C1=CC=CC=C1)=O.O=S(NC2=CC(Cl)=C(C(Cl)=C2)OC3=CN=C4C=CC=CC4=C3)(C5=CC=C(C=C5Cl)Cl)=O
Biological Activity
DescriptionAMG131 benzenesulfonate is a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist, classified as a non-thiazolidinedione (TZD) modulator. It binds to the PPARγ receptor, occupying a unique position in the binding pocket, which allows for distinct interactions compared to traditional TZDs. This compound has demonstrated potential in research pertaining to the treatment of type-2 diabetes mellitus, making it a valuable tool for investigating PPARγ-related metabolic pathways.
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SHIPPING AND STORAGE
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