AMG131 benzenesulfonate
Catalog No. A40109

AMG131 benzenesulfonate is a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist, classified as a non-thiazolidinedione (TZD) modulator. It binds to the PPARγ receptor, occupying a unique position in the binding pocket, which allows for distinct interactions compared to traditional TZDs. This compound has demonstrated potential in research pertaining to the treatment of type-2 diabetes mellitus, making it a valuable tool for investigating PPARγ-related metabolic pathways.
Chemical Information
| Catalog Num | A40109 |
|---|---|
| M. Wt | 672.38 |
| Formula | C27H18Cl4N2O6S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 849738-78-9 |
| Synonyms | INT131 benzenesulfonate |
| SMILES | O=S(O)(C1=CC=CC=C1)=O.O=S(NC2=CC(Cl)=C(C(Cl)=C2)OC3=CN=C4C=CC=CC4=C3)(C5=CC=C(C=C5Cl)Cl)=O |
Biological Activity
| Description | AMG131 benzenesulfonate is a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist, classified as a non-thiazolidinedione (TZD) modulator. It binds to the PPARγ receptor, occupying a unique position in the binding pocket, which allows for distinct interactions compared to traditional TZDs. This compound has demonstrated potential in research pertaining to the treatment of type-2 diabetes mellitus, making it a valuable tool for investigating PPARγ-related metabolic pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


