Product Data Sheet

LTD4 antagonist 3

Catalog No. A40125

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LTD4 antagonist 3 (FK011 hydrochloride) is a selective leukotriene D4 (LTD4) antagonist that also exhibits agonistic activity for peroxisome proliferator-activated receptor gamma (PPAR-γ). This compound demonstrates enhanced PPAR-γ activation with a fold-increase of 1.50 at 1 μM and 2.35 at 10 μM. LTD4 antagonist 3 is valuable for research in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and related therapeutic applications targeting inflammatory pathways.
Chemical Information
Catalog NumA40125
M. Wt457.97
FormulaC24H24ClNO4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.149437-51-4
SynonymsFK011 hydrochloride
SMILESO=C(CC1=C(COC2=CC3=C(OC(C4=NC(C(C)(C)C)=CS4)=C3)C=C2)C=CC=C1)O.Cl
Biological Activity
DescriptionLTD4 antagonist 3 (FK011 hydrochloride) is a selective leukotriene D4 (LTD4) antagonist that also exhibits agonistic activity for peroxisome proliferator-activated receptor gamma (PPAR-γ). This compound demonstrates enhanced PPAR-γ activation with a fold-increase of 1.50 at 1 μM and 2.35 at 10 μM. LTD4 antagonist 3 is valuable for research in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and related therapeutic applications targeting inflammatory pathways.
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