Product Data Sheet
PPARγ agonist 17
Catalog No. A40152
PPARγ Agonist 17 is a selective agonist of the peroxisome proliferator-activated receptor gamma (PPARγ). It enhances PPARγ activity, leading to cell cycle arrest in the G2/M phase, inhibition of cell migration, and induction of apoptosis in HT-29 colorectal cancer cells. This compound exhibits a broad spectrum of anti-proliferative effects against cancer cells while demonstrating relatively low toxicity in normal cells. Additionally, it is important to note that PPARγ Agonist 17 does not cross the blood-brain barrier, making it suitable for specific research applications.
Chemical Information
| Catalog Num | A40152 |
|---|---|
| M. Wt | 766.02 |
| Formula | C48H63NO7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3054652-58-0 |
| Synonyms | |
| SMILES | C[C@]12[C@@](C(C=C3[C@]2(CC[C@@]4([C@@]3([H])C[C@](CC4)(C(O)=O)C)C)C)=O)([H])[C@@]5([C@@](C(C)([C@H](CC5)OC(CC6=CC=CC(NC(COC7=C(C)C=CC(C)=C7)=O)=C6)=O)C)([H])CC1)C |
Biological Activity
| Description | PPARγ Agonist 17 is a selective agonist of the peroxisome proliferator-activated receptor gamma (PPARγ). It enhances PPARγ activity, leading to cell cycle arrest in the G2/M phase, inhibition of cell migration, and induction of apoptosis in HT-29 colorectal cancer cells. This compound exhibits a broad spectrum of anti-proliferative effects against cancer cells while demonstrating relatively low toxicity in normal cells. Additionally, it is important to note that PPARγ Agonist 17 does not cross the blood-brain barrier, making it suitable for specific research applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
