Product Data Sheet

PPARα/γ agonist 2

Catalog No. A40158

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PPARα/γ Agonist 2 is a potent oral activator of PPARα, functioning as a full agonist, and a partial agonist for PPARγ, with EC50 values of 0.95 μM and 0.91 μM, respectively. In addition to its dual agonistic activity, this compound serves as a PTP1B inhibitor, contributing to its role as an anti-diabetic agent. This reagent is essential for research into metabolic disorders, obesity, and type 2 diabetes, aiding in the exploration of therapeutic strategies targeting PPAR pathways.
Chemical Information
Catalog NumA40158
M. Wt368.42
FormulaC25H20O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2213365-56-9
Synonyms
SMILESO=C(C(CC1=CC=CC2=C1C=CC=C2)OC3=CC=C(C4=CC=CC=C4)C=C3)O
Biological Activity
DescriptionPPARα/γ Agonist 2 is a potent oral activator of PPARα, functioning as a full agonist, and a partial agonist for PPARγ, with EC50 values of 0.95 μM and 0.91 μM, respectively. In addition to its dual agonistic activity, this compound serves as a PTP1B inhibitor, contributing to its role as an anti-diabetic agent. This reagent is essential for research into metabolic disorders, obesity, and type 2 diabetes, aiding in the exploration of therapeutic strategies targeting PPAR pathways.
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SHIPPING AND STORAGE
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