Product Data Sheet
Ketopioglitazone
Catalog No. A40175
Ketopioglitazone is a PPARγ agonist, serving as an active metabolite of the antidiabetic agent pioglitazone. It is primarily produced through the metabolism of pioglitazone by the cytochrome P450 isoform CYP2C8. Notably, ketopioglitazone has demonstrated efficacy in lowering blood glucose levels in a KKAy mouse model of type 2 diabetes, making it relevant for research into metabolic disorders and diabetes management.
Chemical Information
| Catalog Num | A40175 |
|---|---|
| M. Wt | 370.42 |
| Formula | C19H18N2O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 146062-45-5 |
| Synonyms | |
| SMILES | O=C(SC1CC2=CC=C(C=C2)OCCC3=NC=C(C=C3)C(C)=O)NC1=O |
Biological Activity
| Description | Ketopioglitazone is a PPARγ agonist, serving as an active metabolite of the antidiabetic agent pioglitazone. It is primarily produced through the metabolism of pioglitazone by the cytochrome P450 isoform CYP2C8. Notably, ketopioglitazone has demonstrated efficacy in lowering blood glucose levels in a KKAy mouse model of type 2 diabetes, making it relevant for research into metabolic disorders and diabetes management. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
