Product Data Sheet
SR-1903
Catalog No. A40182
SR-1903 is an inverse agonist of RORγ and PPARγ, exhibiting IC50 values of approximately 100 nM and 209 nM for these targets, respectively. This compound demonstrates significant anti-inflammatory and anti-diabetic properties, making it valuable in models of collagen-induced arthritis and diet-induced obesity. SR-1903's unique mechanism of action positions it as a useful reagent in researching metabolic disorders and inflammatory diseases.
Chemical Information
| Catalog Num | A40182 |
|---|---|
| M. Wt | 523.51 |
| Formula | C27H27F6N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1414248-06-8 |
| Synonyms | |
| SMILES | OC(C(F)(F)F)(C(F)(F)F)C1=CC=C(C2=CC=C(CN3CCN(CC4=CC=NC=C4)CC3)C=C2C)C=C1 |
Biological Activity
| Description | SR-1903 is an inverse agonist of RORγ and PPARγ, exhibiting IC50 values of approximately 100 nM and 209 nM for these targets, respectively. This compound demonstrates significant anti-inflammatory and anti-diabetic properties, making it valuable in models of collagen-induced arthritis and diet-induced obesity. SR-1903's unique mechanism of action positions it as a useful reagent in researching metabolic disorders and inflammatory diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
