Product Data Sheet
(E/Z)-Elafibranor
Catalog No. A40186
(E/Z)-Elafibranor (also known as (E/Z)-GFT505) is a dual agonist of the peroxisome proliferator-activated receptors alpha (PPARα) and delta (PPARδ), exhibiting EC50 values of 45 nM and 175 nM, respectively. This compound plays a significant role in lipid metabolism and inflammation modulation, making it valuable for research in metabolic disorders, obesity, and non-alcoholic fatty liver disease (NAFLD). Its ability to simultaneously target multiple pathways positions (E/Z)-Elafibranor as a promising candidate for therapeutic interventions in metabolic diseases.
Chemical Information
| Catalog Num | A40186 |
|---|---|
| M. Wt | 384.49 |
| Formula | C22H24O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 824932-88-9 |
| Synonyms | (E/Z)-GFT505 |
| SMILES | O=C(C(C)(C)OC1=C(C)C=C(/C=C/C(C2=CC=C(C=C2)SC)=O)C=C1C)O |
Biological Activity
| Description | (E/Z)-Elafibranor (also known as (E/Z)-GFT505) is a dual agonist of the peroxisome proliferator-activated receptors alpha (PPARα) and delta (PPARδ), exhibiting EC50 values of 45 nM and 175 nM, respectively. This compound plays a significant role in lipid metabolism and inflammation modulation, making it valuable for research in metabolic disorders, obesity, and non-alcoholic fatty liver disease (NAFLD). Its ability to simultaneously target multiple pathways positions (E/Z)-Elafibranor as a promising candidate for therapeutic interventions in metabolic diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
