Product Data Sheet
N-Octadecyl-N'-propyl-sulfamide
Catalog No. A40199
N-Octadecyl-N'-propyl-sulfamide is a selective agonist of peroxisome proliferator-activated receptor alpha (PPARα), demonstrating an EC50 of 100 nM. As an analog of oleoylethanolamide (OEA), it activates PPARα, playing a critical role in lipid and glucose metabolism. In animal models, the compound significantly reduces food intake and body weight gain, with a notable effect observed in both free-feeding Wistar rats and obese Zucker (fa/fa) rats, particularly at doses of 1 mg/kg. Additionally, a dose of 10 mg/kg administered intraperitoneally effectively inhibits appetite and lowers plasma triglyceride levels.
Chemical Information
| Catalog Num | A40199 |
|---|---|
| M. Wt | 390.67 |
| Formula | C21H46N2O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 925891-74-3 |
| Synonyms | |
| SMILES | CCCCCCCCCCCCCCCCCCNS(=O)(NCCC)=O |
Biological Activity
| Description | N-Octadecyl-N'-propyl-sulfamide is a selective agonist of peroxisome proliferator-activated receptor alpha (PPARα), demonstrating an EC50 of 100 nM. As an analog of oleoylethanolamide (OEA), it activates PPARα, playing a critical role in lipid and glucose metabolism. In animal models, the compound significantly reduces food intake and body weight gain, with a notable effect observed in both free-feeding Wistar rats and obese Zucker (fa/fa) rats, particularly at doses of 1 mg/kg. Additionally, a dose of 10 mg/kg administered intraperitoneally effectively inhibits appetite and lowers plasma triglyceride levels. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
