Product Data Sheet

Chk2-IN-2

Catalog No. A40228

main product photo
Chk2-IN-2 is a selective inhibitor of CHK2, a key regulator in the DNA damage response pathway. This compound exhibits potent anticancer activity by hindering cell cycle progression in response to DNA damage. It is primarily utilized in research applications focused on cancer cell biology and the development of targeted therapies for tumors with defective DNA repair mechanisms.
Chemical Information
Catalog NumA40228
M. Wt482.41
FormulaC20H19F5N8O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2984543-29-3
Synonyms
SMILESFC1=C(C2=NC(C(N[C@H]3C[C@@H](CNC3)F)=O)=C(N=C2)N)C=C(C4=CN(N=C4)CC(F)(F)F)N=C1
Biological Activity
DescriptionChk2-IN-2 is a selective inhibitor of CHK2, a key regulator in the DNA damage response pathway. This compound exhibits potent anticancer activity by hindering cell cycle progression in response to DNA damage. It is primarily utilized in research applications focused on cancer cell biology and the development of targeted therapies for tumors with defective DNA repair mechanisms.
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SHIPPING AND STORAGE
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