Product Data Sheet

HLDA-221

Catalog No. A40284

main product photo
HLDA-221 is a non-covalent regulated induced proximity targeting agent (RIPTAC) that selectively binds to BRD4-BD1 upon pre-incubation with FKBP. This compound facilitates protein-protein interactions, making it a valuable tool for studying cellular signaling pathways and gene regulation. HLDA-221 has potential applications in cancer research, particularly in understanding the role of BRD4 in tumorigenesis and therapeutic targeting.
Chemical Information
Catalog NumA40284
M. Wt1220.86
FormulaC64H78ClN7O13S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3077339-82-0
Synonyms
SMILESCC(C(C(C(C=C1)=CC=C1Cl)=N[C@H]2CC(NCCOCCOCCN(C(COC3=CC=CC([C@@H](CCC4=CC(OC)=C(OC)C=C4)OC([C@@H]5CCCCN5C([C@H](C6=CC(OC)=C(OC)C(OC)=C6)CC)=O)=O)=C3)=O)C)=O)=C(S7)N8C2=NN=C8C)=C7C
Biological Activity
DescriptionHLDA-221 is a non-covalent regulated induced proximity targeting agent (RIPTAC) that selectively binds to BRD4-BD1 upon pre-incubation with FKBP. This compound facilitates protein-protein interactions, making it a valuable tool for studying cellular signaling pathways and gene regulation. HLDA-221 has potential applications in cancer research, particularly in understanding the role of BRD4 in tumorigenesis and therapeutic targeting.
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SHIPPING AND STORAGE
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